Due to Legal and Ethical considerations, creating embryos of desired sex using pre-implantation genetic screening is not possible. When embryos are created via in vitro fertilization and then screened for gender selection, approximately half of your embryos will end up being the "undesired sex", which means they would be destroyed. In order to avoid this problem, we use MicroSort as a gender selection method.
Pre-Implantation Genetic Screening (PGD or PGS) is not used as a gender selection method. However, in older age brackets, The aging oocyte (egg) is associated with several problems including mitochondrial dysfunctions, aneuploidy and epigenetic changes. In order to make sure that your embryos do not suffer from a chromosomal aneuploidy (abnormality), it is recommended that patients over the age of 30 have PGS screening for their embryos after MicroSort gender (sex) selection has been performed. The diagram below shows the percentage of embryos that will possess a chromosomal abnormality at various age groups.
In natural pregnancies, genetically abnormal embryos either eliminate themselves at very early stages of pregnancy without the pregnant woman even noticing, or cause early miscarriages prior to 12 weeks of gestation. In order to avoid this incidence, we recommend using PGS. PGS will eliminate the likelihood of transferring a genetically abnormal child. The additional cost of PGS on top of MicroSort IVF treatment is 2,500 Euros.
This option is the least invasive gender selection option for fertile and younger couples who would like to specify the sex of their next child for family balancing purposes. The MicroSort sperm sorting technology is coupled with the IUI (Intra-Uterine Insemination) method in order to assist couples to conceive a child of desired sex. Once the sperm sample is processed into X and Y bearing cells, the cells carrying the chromosome for desired sex will be injected intra-uterine so that they can move around and fertilize the mature eggs.
The IUI procedure itself is one of the least invasive fertility treatment options. As such, it does not allow us to do much inside the laboratory in terms of fertilization or embryo manipulation. This means that while it will offer a higher chance of success compared to intercourse, it will offer a much lower chance of success compared to IVF treatments. Due to its lower level of success chance compared to IVF treatments, IUI is usually recommended for fertile couples in their 20s or perhaps early 30s. After 30 years of age, success rates with IUI treatment will drop substantially, making it an ineffective method of treatment for couples in higher age brackets.
MicroSort (R) Technologies: MicroSort is a patented sperm sorting technology which allows us to sort the sperm into X and Y bearing cells. In other words, we are able to sort the sperm into male and female bearing cells before proceeding with any treatment. However, MicroSort procedures requires that the sperm is within certain parameters. There are restrictions with respect to sperm count, concentration, motility and morphology in order for a sperm sample to qualify for the MicroSort procedure. In order to make sure that the male partner's sperm parameters are sufficient for our sex selection program, we will need to see the male partner's semen analysis report so that an assessment can be made.
Any given sperm sample is likely to contain similar amounts of sperm which carry the X chromosome (the chromosome which is responsible for producing a female offspring) and the Y chromosome (the chromosome which is responsible for producing a male offspring). MicroSort is a mechanical procedure that helps separate sperm cells into two separate compartments as X and Y bearing sperm cells. Once the MicroSort procedure is completed, the relevant sperm sample sorted into the relevant compartment is used during the IVF cycle in order to produce embryos of desired sex.
Sperm samples sorted by MicroSort technologies can be used in a wide range of assisted reproduction techniques, including intra-uterine insemination (IUI), in vitro fertilization (IVF), intracytoplasmic sperm injection (ICSI), and preimplantation genetic diagnosis (PGD).
Only MicroSort laboratories have the technology to perform this precise sperm sorting procedure, and this technology is offered in collaboration with only a limited number of clinics and physicians around the world. This technology is provided solely by North Cyprus IVF Center in Europe and the Middle East.
Even if you do not have any infertility problems and you are able to conceive naturally on your own, gender selection will still require you to undergo infertility testing so that we can make an assessment of your unique fertility level so that our specialists can identify the right protocol of treatment suited for you. This is the most important step before having treatment. At North Cyprus IVF Clinic, we offer a number of gender selection treatment options and deciding which option is better suited for you will depend on a number of factors. These are as follows:
Based on your unique assessment, we will be able to design a suitable treatment protocol aiming to optimize the outcome of your treatment.
With this treatment option, the sperm sorting process is still the same. The sperm sample is sorted into X and Y bearing cells. In this case, given that the patients are undergoing an IVF cycle, the mature eggs are collected from the ovaries so that they can be fertilized with the sorted sperm sample in the laboratory. The IVF part of this treatment option is exactly like the IVF/ICSI treatement. Given that an IVF cycle allows us to obtain a good number of eggs from the female patient, it gives us a chance to create several embryos that are of desired sex so that the highest quality embryos can be transferred into the uterus in order to improve chances of success with pregnancy.
One of the treatment options offered at North Cyprus IVF Clinic is gender selection. Couples may choose gender selection treatment for a number of reasons. A couple may already have children but they may want to select the sex of their next child for family balancing purposes. Alternatively, a couple may want to opt for gender selection for genetic disease prevention purposes in cases where a certain sex may have a predisposition to certain genetic linked diseases.
The increase in chromosomal abnormalities becomes very sharp after the age of 33. Around the age of 37, 40% of embryos obtained via IVF treatment are likely to have a genetic abnormality while this number goes up to about 55% at the age of 41, meaning more than half of the embryos will have a genetic problem. PGS allows us to screen the chromosomes of your embryos and select the ones which do not have any genetic abnormalities. PGS not only allows you to have an improved chance of success by eliminating the defected embryos, but also minimizes the risk of having a child with a genetic problem.